Detailed Abstract
[E-poster - Liver (Transplantation)]
[EP 047] Efficacy And Safety Of Adhesion Barrier In Living-donor Liver Transplantation With Right Liver Graft To Prevent Delayed Gastric Emptying
Sang-Hoon KIM1 , Dong-Hwan JUNG*1 , Sung-Gyu LEE1 , Shin HWANG1 , Chul-Soo AHN1 , Ki-Hun KIM1 , Deok-Bog MOON1 , Tae-Yong HA1 , Gi-Won SONG1 , Gil-Chun PARK1 , Young-In YOON1 , Woo-Hyung KANG1 , Hwui-Dong CHO1 , Su-Min HA1 , Byeong-Gon NA1 , Minjae KIM1 , Sung-Min KIM1 , Geunhyeok YANG1 , Rak-Kyun OH1
1 Division Of Liver Transplantation And Hepatobiliary Surgery, Department Of Surgery, Asan Medical Center, University Of Ulsan College Of Medicine, Seoul, REPUBLIC OF KOREA
Background : Delayed gastric emptying is a common complication of liver transplantation. This study aimed to clarify the efficacy and safety of the application of an adhesion barrier for preventing delayed gastric emptying in living-donor liver transplantation.
Methods : This retrospective study included 453 patients who underwent living-donor liver transplantation using a right lobe graft between January 2018 and August 2019, and the incidence of postoperative delayed gastric emptying and complications was compared between patients in whom adhesion barrier was used (n=179 patients) and those in whom adhesion barrier was not used (n=274 patients). We performed 1:1 propensity score matching between the two groups, and 179 patients were included in each group. Delayed gastric emptying was defined according to the International Study Group for Pancreatic Surgery classification.
Results : The use of adhesion barrier was significantly associated with a lower overall incidence of postoperative delayed gastric emptying in liver transplantation (30.7 vs 17.9%; p=0.002), including grades A (16.8 vs 9.5%; p=0.03), B (7.3 vs 3.4%; p=0.08), and C (6.6 vs. 5.5%; p=0.50). After propensity score matching, similar results were observed for the overall incidence of delayed gastric emptying (29.6 vs 17.9%; p=0.009), including grades A (16.8 vs 9.5%; p=0.04), B (6.7 vs. 3.4%; p=0.15), and C (6.1 vs 5.0%; p=0.65). Univariate and multivariate analyses showed a significant correlation between the use of adhesion barrier and a low incidence of delayed gastric emptying. There were no statistically significant differences in postoperative complications between the two groups.
Conclusions : The application of an adhesion barrier could be a safe and feasible method to reduce the incidence of postoperative delayed gastric emptying in living-donor liver transplantation.
Methods : This retrospective study included 453 patients who underwent living-donor liver transplantation using a right lobe graft between January 2018 and August 2019, and the incidence of postoperative delayed gastric emptying and complications was compared between patients in whom adhesion barrier was used (n=179 patients) and those in whom adhesion barrier was not used (n=274 patients). We performed 1:1 propensity score matching between the two groups, and 179 patients were included in each group. Delayed gastric emptying was defined according to the International Study Group for Pancreatic Surgery classification.
Results : The use of adhesion barrier was significantly associated with a lower overall incidence of postoperative delayed gastric emptying in liver transplantation (30.7 vs 17.9%; p=0.002), including grades A (16.8 vs 9.5%; p=0.03), B (7.3 vs 3.4%; p=0.08), and C (6.6 vs. 5.5%; p=0.50). After propensity score matching, similar results were observed for the overall incidence of delayed gastric emptying (29.6 vs 17.9%; p=0.009), including grades A (16.8 vs 9.5%; p=0.04), B (6.7 vs. 3.4%; p=0.15), and C (6.1 vs 5.0%; p=0.65). Univariate and multivariate analyses showed a significant correlation between the use of adhesion barrier and a low incidence of delayed gastric emptying. There were no statistically significant differences in postoperative complications between the two groups.
Conclusions : The application of an adhesion barrier could be a safe and feasible method to reduce the incidence of postoperative delayed gastric emptying in living-donor liver transplantation.
SESSION
E-poster
E-Session 03/23 ~ 03/25 ALL DAY