Detailed Abstract
[E-poster - Liver (Transplantation)]
[EP 049] Donor Safety And Risk Factors Of Pure Laparoscopic Living Donor Right Hepatectomy: A Korean Multicenter Study
Sang-Hoon KIM1 , Ki-Hun KIM*1 , Kyung-Suk SUH1 , Suk Kyun HONG1 , Gyu-Seong CHOI1 , Jaryung HAN1 , Hwui-Dong CHO1 , Jong Man KIM1 , Young Seok HAN1 , Jai Young CHO1 , Choon Hyuck David KWON1 , Kwang-Woong LEE1 , Ho-Seong HAN1
1 Division Of Liver Transplantation And Hepatobiliary Surgery, Department Of Surgery, Asan Medical Center, University Of Ulsan College Of Medicine, Seoul, REPUBLIC OF KOREA
Background : The aim was to identify safety and risk factors of living donor after pure laparoscopic donor right hepatectomy (PLRDH) in a Korean multicenter cohort study.
Methods : This retrospective study included 543 patients undergoing PLRDH between 2010 and 2018 in five Korean transplantation centers. Rate of complication was assessed and multivariate logistic regression analyses were performed to identify risk factors of open conversion, overall complications, major complications, and biliary complications.
Results : Regarding open conversion, the incidence was 1.7% and the risk factor was body mass index (BMI) >30 kg/m2 (P=0.001, odds ratio [OR] 22.72, 95% confidence interval [CI] 3.56–146.39). Overall, major (Clavien-Dindo classification III-IV), and biliary complication rate were 9.2%, 4.4%, and 3.5%, respectively. For overall complication, risk factors were graft weight >700 g (P=0.007, OR 2.66, 95% CI 1.31–5.41), estimated blood loss (P<0.001, OR 4.84, 95% CI 2.50–9.38), and operation time >400 minutes (P=0.01, OR 2.46, 95% CI 1.25–4.88). For major complication, risk factors were graft weight >700 g (P=0.002, OR 4.01, 95% CI 1.67–9.62) and operation time >400 minutes (P=0.003, OR 3.84, 95% CI 1.60–9.21). For biliary complications, risk factors were graft weight >700 g (P=0.01, OR 4.34, 95% CI 1.40–13.45) and operation time >400 minutes (P=0.01, OR 4.16, 95% CI 1.34–12.88).
Conclusions : Careful donor selection for PLRDH considering BMI, graft weight, estimated blood loss, and operation time combined with skilled procedure can improve donor safety.
Methods : This retrospective study included 543 patients undergoing PLRDH between 2010 and 2018 in five Korean transplantation centers. Rate of complication was assessed and multivariate logistic regression analyses were performed to identify risk factors of open conversion, overall complications, major complications, and biliary complications.
Results : Regarding open conversion, the incidence was 1.7% and the risk factor was body mass index (BMI) >30 kg/m2 (P=0.001, odds ratio [OR] 22.72, 95% confidence interval [CI] 3.56–146.39). Overall, major (Clavien-Dindo classification III-IV), and biliary complication rate were 9.2%, 4.4%, and 3.5%, respectively. For overall complication, risk factors were graft weight >700 g (P=0.007, OR 2.66, 95% CI 1.31–5.41), estimated blood loss (P<0.001, OR 4.84, 95% CI 2.50–9.38), and operation time >400 minutes (P=0.01, OR 2.46, 95% CI 1.25–4.88). For major complication, risk factors were graft weight >700 g (P=0.002, OR 4.01, 95% CI 1.67–9.62) and operation time >400 minutes (P=0.003, OR 3.84, 95% CI 1.60–9.21). For biliary complications, risk factors were graft weight >700 g (P=0.01, OR 4.34, 95% CI 1.40–13.45) and operation time >400 minutes (P=0.01, OR 4.16, 95% CI 1.34–12.88).
Conclusions : Careful donor selection for PLRDH considering BMI, graft weight, estimated blood loss, and operation time combined with skilled procedure can improve donor safety.
SESSION
E-poster
E-Session 03/23 ~ 03/25 ALL DAY