Detailed Abstract
[BP Poster Presentation 1 - Biliary & Pancreas (Biliary Disease/Surgery)]
[BP PP 1-4] Effect Of Postoperative Glycemic Control On Survival Rates Following Pancreaticoduodenectomy In Patients With Biliary Tract Cancer
Jangho PARK1 , Sang-Jae PARK*2 , Sung-Sik HAN2 , Mee Joo KANG2 , Hyeong Min PARK2
1 Department Of General Surgery, Osan Hankook Hospital, REPUBLIC OF KOREA
2 Center For Liver & Pancreato-biliary Cancer,, National Cancer Center, REPUBLIC OF KOREA
Background : Poor postoperative glycemic control in diabetic patients was reported to affect the decrease in survival of bladder and pancreatic cancers, but there were no studies regarding bile duct cancer. We investigated overall and recurrence-free survivals of patients who underwent pancreatoduodenectomy for bile duct cancer.
Methods : From April 2013 to December 2018, 50 patients performed pancreatoduodenectomy due to bile duct cancer. The patients were divided into two groups based on HbA1c of 6.5% measured 3 to 6 months following surgery: (1) Patients with HbA1c < 6.5% (2) Patients with HbA1c ≥ 6.5%. Overall and recurrence-free survivals were compared between those two groups. In addition, patients with diabetes were divided according to the same criteria and analyzed.
Results : Recurrent-free survival was longer in patients with postoperative HbA1c < 6.5% than in patients with postoperative HbA1c ≥ 6.5% (61.0 months vs. 12.0 months; p=0.074). Among patients diagnosed with diabetes before the operation, overall survival was also longer in patients with postoperative HbA1c < 6.5% than in patients with postoperative HbA1c ≥ 6.5% (98.0 ± 0.0 months vs. 44.7 ± 10.6 months; p=0.054).
Conclusions : In patients who underwent pancreaticoduodenectomy for biliary duct cancer, poor postoperative glycemic control affects the survival rate.
Methods : From April 2013 to December 2018, 50 patients performed pancreatoduodenectomy due to bile duct cancer. The patients were divided into two groups based on HbA1c of 6.5% measured 3 to 6 months following surgery: (1) Patients with HbA1c < 6.5% (2) Patients with HbA1c ≥ 6.5%. Overall and recurrence-free survivals were compared between those two groups. In addition, patients with diabetes were divided according to the same criteria and analyzed.
Results : Recurrent-free survival was longer in patients with postoperative HbA1c < 6.5% than in patients with postoperative HbA1c ≥ 6.5% (61.0 months vs. 12.0 months; p=0.074). Among patients diagnosed with diabetes before the operation, overall survival was also longer in patients with postoperative HbA1c < 6.5% than in patients with postoperative HbA1c ≥ 6.5% (98.0 ± 0.0 months vs. 44.7 ± 10.6 months; p=0.054).
Conclusions : In patients who underwent pancreaticoduodenectomy for biliary duct cancer, poor postoperative glycemic control affects the survival rate.
SESSION
BP Poster Presentation 1
Poster Presentation 3/24/2023 2:50 PM - 3:50 PM