Detailed Abstract
[E-poster - Liver (Liver Disease/Surgery)]
[EP 010] Magnetic Resonance Elastography Predicts De Novo Recurrence After Resection For Hepatocellular Carcinoma
Sanggyun SUH1 , Kwang-Woong LEE*2 , Sola LEE2 , Su Young HONG2 , Eui Soo HAN3 , Suk Kyun HONG1 , YoungRok CHOI1 , Nam-Joon YI1 , Kyung-Suk SUH1
1 Department Of Surgery, Chung-Ang University Gwangmyeong Hospital, REPUBLIC OF KOREA
2 Department Of Surgery, Seoul National University College Of Medicine, REPUBLIC OF KOREA
3 Department Of Surgery, The Catholic University Of Korea, Uijeongbu ST. Mary’s Hospital, REPUBLIC OF KOREA
Background : Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. The best curative treatment for hepatocellular carcinoma is liver resection. But, , it has been known that there is a high possibility of recurrence if there is cirrhosis even after liver resection. Most HCC patients has liver fibrosis/cirrhosis. Magnetic resonance elastography (MRE) acqure images that can be referred for LSM and a larger sampling area.
Methods : Between January 2014 and December 2018, 603 patients underwent Hepatic resection (HR) for HCC. Among 603 patients, 245 patient checked MRE, but 5 cases had technical failure. We analyzed 241 patients. HCC recurrence was defined according to previous studies and the recent AASLD guidelines as early (if occurring <24 months) or late (if occurring >24 months). The follow-up protocol included a clinical assessment by physical examination, US and laboratory exams every 3 months. HCC recurrence was diagnosed according to modifications of alpha-fetoprotein levels and US appearance, confirmed either by multiphasic CT or multiphasic MRI. Clinical data were analyzed disease-free survival rate (DFSR) according to serum alpha-fetoprotein (AFP) level, Magnetic resonance elastography (MRE).
Results : Between January 2014 and December 2018, HR for HCC group has incidence of recurrence is 40.2% (97/241). Early recurrence rate is 22.0% (53/241) rate recurrent rate is 18.3% (44/241).
Conclusions : Magnetic resonance elastography that measure liver fibrosis predict de novo recurrence after hepatic resection for hepatocellular carcinoma. So we consider liver transplantation in severe stiffness liver parenchyma
Methods : Between January 2014 and December 2018, 603 patients underwent Hepatic resection (HR) for HCC. Among 603 patients, 245 patient checked MRE, but 5 cases had technical failure. We analyzed 241 patients. HCC recurrence was defined according to previous studies and the recent AASLD guidelines as early (if occurring <24 months) or late (if occurring >24 months). The follow-up protocol included a clinical assessment by physical examination, US and laboratory exams every 3 months. HCC recurrence was diagnosed according to modifications of alpha-fetoprotein levels and US appearance, confirmed either by multiphasic CT or multiphasic MRI. Clinical data were analyzed disease-free survival rate (DFSR) according to serum alpha-fetoprotein (AFP) level, Magnetic resonance elastography (MRE).
Results : Between January 2014 and December 2018, HR for HCC group has incidence of recurrence is 40.2% (97/241). Early recurrence rate is 22.0% (53/241) rate recurrent rate is 18.3% (44/241).
Conclusions : Magnetic resonance elastography that measure liver fibrosis predict de novo recurrence after hepatic resection for hepatocellular carcinoma. So we consider liver transplantation in severe stiffness liver parenchyma
SESSION
E-poster
E-Session 03/23 ~ 03/25 ALL DAY